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premature ejaculation pills priligy
Description: product form, composition
priligy pills film-coated, round, biconvex, with extruded says "30" or "60" inside a triangle on one side; the cross-section of the Tablet core white, or almost white.
-dapoxetine (in the form of hydrochloride) 30 mg or 60 mg
Excipients: lactose monohydrate, microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, magnesium stearate.
Composition of membrane shell: lactose monohydrate, hypromellose, titanium dioxide (E171), triacetin, stain iron oxide black (Đ172), iron oxide yellow (Đ172).
Pharmacological group: medication for the treatment of premature ejaculation.
Farmdejstvie: Dapoxetine is a unique, short-acting, selective serotonin reuptake inhibitor (SSRI). Clinically proven, that the drug is effective in the treatment of premature ejaculation in males aged 18 years and older. Approximately 27-34% of men of all ages suffer from premature ejaculation, reception Dapoksetina prolongs the duration of sexual intercourse in 3-4 times.
SSRIs block the receptors in the brain, absorbing serotonin acting selectively and delaying ejaculation. Unlike other drugs sparingly and selectively delaying ejaculation. Unlike other drugs sparingly and selectively delaying ejaculation. Unlike other medications selective
Indications:-for the treatment of premature ejaculation in men aged 18 to 64 years.
Category actions on the fetus: the drug priligy is not intended for use in women.
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Based on the limited amount of data from clinical trials, there is no reason to assume that dapoksetina man can affect pregnancy partner. Well-controlled studies of application of dapoksetina in pregnant women has been carried out.
It is unknown whether dapoxetine and its metabolites in breast milk.
Contraindications: hypersensitivity to dapoksetina gidrohloridu or any auxiliary component of the drug. expressed by heart disease (e.g., congestive heart failure II-IV class NYHA, heart disorders conductivity (AV-blokada 2-3 degree or SSSU) in the absence of Permanent pacemaker expressed CHD or defeat pump apparatus); the simultaneous admission of MAO inhibitors and reception within 14 days after the termination of their use. Similarly, MAO inhibitors should not be taken during 7 days after discontinuation of the drug priligy;
-simultaneous tioridazina and within 14 days after the termination of its use. Similarly, thioridazine should not be taken within 7 days after discontinuation of the drug priligy;
-simultaneous reception of serotonin reuptake inhibitors (selective serotonin reuptake inhibitors-SSRI), inhibitors of reverse takeover serotonin and norarenalina and tricyclic antidepressants) and other drugs with serotonergic activity (e.g., L-tryptophan, triptans, tramadol, linezolid, lithium, preparations of St. John's wort (Hypericum wort) and within 14 days after you stop taking these drugs. Similarly, these drugs should not be taken within 7 days after discontinuation of the drug priligy;
-simultaneous reception with active CYP3A4 inhibitors, such as ketoconazole, ritonavir, itrakonazolom, sakvinavirom, telitromicinom, nefazodonom, nelfinavirom, atazanavir, etc.;
moderate and severe violations of the liver;
-serious violations of the kidneys;
children and adolescents under the age of 18 years;
is lactose intolerance.
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If there is a history of the established or suspected orthostatic hypotension, as well as having a history of mania/hypomania or bipolar disorder treatment should be avoided.
-weak or moderately expressed violations kidney function;
-simultaneous application with powerful inhibitors izofermenta CYP3A4 inhibitors and moderate CYP2D6 in patients with low activity genotipiceski izofermenta CYP2D6 and patients with high activity izofermenta CYP2D6 (in combination with moderate inhibitors izofermenta CYP3A4);
-the simultaneous use of drugs that affect platelet aggregation, and with an anticoagulant because of the risk of bleeding.
Dosage: for oral use. The tablet should be swallowed whole, with at least one full glass of water. Product priligy can be taken regardless of the meal.
Adult males from 18 to 64 years old:
The recommended initial dose for all males is 30 mg; This dose taken for 1-3 hours before sexual intercourse. Insufficient effect and good endurance dose 30 mg can be increased to 60 mg.
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Description of individual side effects:
Fainting with loss of consciousness, with bradycardia or stopover site sinussovogo have been observed in patients with holterovskom and monitorirovanii have been reported in clinical studies. The data is regarded as an undesirable phenomena associated with the use of the drug. Most of the cases were observed during the first 3:00 after taking the drug, after taking the first dose or associated with medical procedures (collection of blood, body position changes, measurement of HELL). Prodromal?nye symptoms are often preceded by faint.
The incidence of syncope and prodromal?nyh symptoms depend on the dose that was demonstrated in patients receiving higher doses of the drug priligy.
Effects of withdrawal:
With the sudden cancellation of a long-used selective serotonin reuptake inhibitors for the treatment of chronic depessivnyh disorder observed the following symptoms: dysphoric State, irritability, psychomotor agitation, dizziness, sensory disorders (e.g. paresthesia), anxiety, confusion, headache, lethargy, emotional lability, insomnia, and hypomania. The results of the study showed a higher frequency of security of withdrawal symptoms as insomnia and dizziness of mild and moderate degree after the drug after 62 days of use.
Overdose: in clinical studies overdose not described.
Admission drug dose priligy to 240 mg (120 doses 2 mg at intervals of 3 h) did not cause unforeseen adverse events. Generally, SSRI overdose symptoms include serotoninergicakie reactions, including somnolence, gastrointestinal disorders (nausea, vomiting), tachycardia, tremor, agitation, and dizziness.
In overdose should, if necessary, carry out standard supportive care. Due to the significant drug binding to plasma proteins and the large volume of distribution of dapoksetina hydrochloride forced diuresis, dialysis, blood transfusions and gemoperfuzia are unlikely to be effective. Specific antidote unknown.
Interactions: do not take Dapoxetine from any of the following drugs:
Medications used to treat depression called "monoamine oxidase inhibitors" (MAOIs);
other drugs used to treat depression;
drugs used in the treatment of schizophrenia;
Lithium medications for treatment of bipolar disorder (Kerry Katona);
St. John's wort is a herbal medicine;
Tramadol is a powerful analgesic;
drugs used to treat migraines.
You should not take Dapoxetine from at the same time as any of the above drugs. In addition, you must stop the reception of these drugs for 14 days before you start taking Dapoksetina.
Within 7 days after reception of the Dapoksetina are not allowed to treat any of the following medicines:
some drugs used to treat fungal infections, including ketoconazole and itraconazole;
drugs used to treat HIV infection, including ritonavir, nelfinavir and atazanavir;
medications used to treat the infection, including telithromycin;
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Do not take Dapoxetine, if you are taking any of the drugs mentioned above. Be sure to consult your doctor if you should take other medicines along with taking the pill Dapoksetina.
Not recommended reception alcohol Dapoksetina, under the influence of alcohol may be amplified side effects that can lead to increased risk to your health.
You should also consult with your doctor before you take Dapoksetina if:
have you ever had any mental disorder;
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you have blood clotting problems, kidney disease, epilepsy or dizziness, low blood pressure.
Before you start taking Dapoxetine need to check blood pressure, it should not be sliskomnizkim.
Special instructions: General:
The drug priligy is intended only for men with premature ejaculation. The safety of the drug in men without premature ejaculation is not installed, no ejaculation latency data.
The reception together with drugs:
Patients should be advised not to take the drug together with priligy drugs. Admission drug priligy drugs with serotonergic activity, such as ketamine, methylenedioxymethamphetamine (MDMA) and lysergic acid dietilamidom (LSD) can lead to potentially serious reactions, including, but not limited to, fibrillation, hyperthermia and serotoninergic syndrome. The admission of the drug priligy in conjunction with sedatives, such as opiates or benzodiazepines, may increase drowsiness and dizziness.